Screening of Antimicrobial Activity and Polyketide Synthase Gene Identification from the Actinomycetes Isolates

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چکیده

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Detection and Relation of Polyketide Synthase (PKSs) Genes With Antimicrobial Activity in Terrestrial Cyanobacteria of Lavasan

Background and Aims: Cyanobacteria are considered as favorable source for new pharmaceutical compounds. To date, the majority of bioactive metabolites isolated from cyanobacteria are either polyketides (PKSs) or non-ribosomal peptides. Despite of several worldwide studies on prevalence of PKSs, none of them included the terrestrial cyanobacteria of the Lavasan. Therefore, this study aimed to de...

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The search for novel bioactive compounds from the natural environment has rapidly been gaining momentum with the increase in multi-drug resistant (MDR) pathogens. In the present study, the antimicrobial potential of novel actinomycetes has been evaluated by initial screening of six soil samples. Primary and secondary screening was performed against Bacillus subtilis, Staphylococcus aureus, Esch...

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antioxidant and antimicrobial activity of allium jesdianum extract

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Investigation of bacteria with polyketide synthase genes and antimicrobial activity isolated from South China Sea sponges.

AIMS To obtain bacteria with PKS (polyketide synthase) genes and antimicrobial activity from sponges. METHODS AND RESULTS Eighteen bacteria with KS (ketosynthase) genes were identified by polymerase chain reaction (PCR) screening of 98 isolates from South China Sea sponges, Stelletta tenuis, Halichondria rugosa, Dysidea avara and Craniella australiensis. 16S rRNA gene-based Blast analysis ind...

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ژورنال

عنوان ژورنال: Journal of Microbial & Biochemical Technology

سال: 2018

ISSN: 1948-5948

DOI: 10.4172/1948-5948.1000404